马小京

姓名: 马小京

职称: 教授

E-Mail: Xim2002@sjtu.edu.cn

个人主页:

联系电话: 021-3420-5287

  • 个人简历:

    个人简介

     

    马小京,男,博士,“盛毓绶”讲习教授,生命科学技术学院副院长,“盛毓绶细胞与免疫学中心”主任,博士生导师。1987年年于英国爱丁堡大学获得分子遗传学博士学位后,赴美国宾夕法尼亚大学麦从事博士后和研究助理工作。然后在美国康耐尔大学医学院任微生物和免疫学系助理教授,副教授和终身教授。迄今共发表SCI论文90篇。

    教育经历

     

    1987.12-1992.12  美国宾西法尼亚大学  Wistar研究所   博士后

    1983.10-1987.11  英国爱丁堡大学      遗传学系        博士

    1978.3-1982.2    北京农业大学        畜牧系          学士

    工作经历

     

    2011.7-至今     上海交通大学生命科学技术学院 国家“千人计划”第四批入选者  上海交通大学“盛毓绶”冠名讲席教授

    2007.10-2011.06 美国康奈尔大学医学院 微生物与免疫系 终身教授

    2004.04-2007.09 美国康奈尔大学医学院 微生物与免疫系 副教授

    2000.03-2004.03 美国康奈尔大学医学院 微生物与免疫系 助理教授

    1996-1999       美国宾西法尼亚大学   Wistar研究所 助理研究员

    1993-1995       美国宾西法尼亚大学   Wistar研究所 研究助理

    荣誉奖励

     

    2012 Excellence in Teaching Award” by Weill Cornell Medical College

    1999-2004 Howard Temin Award (NCI/NIH)

    1998        Young Investigators Award by International Cytokine Society.

    1985-1987 Overseas Student Award by the British Council.

    1983-1987   Predoctoral Studentship from Tang Kakji Trust.

    Editorial Responsibilities

    2013.5-present Editorial Board  Genes and Immunity

    2012.7-present  Member  F1000 Research Editorial Board

    2009.12-present Advisory Editorial Board of Cellular and Molecular Immunology

    2009.7-present Associate Editor  The Journal of Immunology

    2007-present     Editorial Board, Journal of the International Society of Interferon and Cytokine Research

    2005-present     Advisory Editorial Board of Annual Review of Biomedical Sciences

    2002-2012     Advisory Editorial Board of the Journal of Experimental Medicine 

    2002-present     Member, Faculty 1000 (Immunology)

     

     

     

     

     

     

     

  • 1. 巨噬细胞的吞噬凋亡细胞的功能和免疫作用

    2. 自身免疫性炎症性肠道疾病的病理学机制

    3. 三阴性乳腺癌的肿瘤免疫学研究

  • 1. Murray HW, Zhang Y, Zhang Y, Raman VS, Reed SG, Ma X. Regulatory Actions of TLR2 and TLR4 in Leishmania donovani Infection in the Liver. Infect Immun. 2013 Apr 15. [Epub ahead of print]

    2. Yin F, Banerjee R, Thomas B, Zhou P, Qian L, Jia T, Ma X, Ma Y, Iadecola C, Beal MF, Nathan C, Ding A. Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice. J Exp Med. 2010, 207(1):117-128.
    3. Kang X, Kim HJ, Ramirez M, Salameh S, Ma X. The septic shock-associated IL-10 -1082 A > G polymorphism mediates allele-specific transcription via poly (ADP-Ribose) polymerase 1 in macrophages engulfing apoptotic cells. J Immunol, 2010, 184(7):3718-3724.
    4. Zhang Y, Ma X. Triptolide inhibits IL-12/IL-23 expression in APCs via CCAAT/enhancer-binding protein alpha. J Immunol, 2010, 184(7):3866-77.
    5. Murray HW, Xiang Z, Ma X. Responses to Leishmania donovani in mice deficient in both phagocyte oxidase and inducible nitric oxide synthase. Am J Trop Med Hyg, 2006, 74(6):1013-5.
    6. Murray HW, Tsai CW, Liu J, Ma X. Visceral Leishmania donovani infection in interleukin-13-/- mice. Infect Immun 2006, 74(4):2487-2490.
    7. Liu J, Ma X. Interferon regulatory factor 8 regulates RANTES gene transcription in cooperation with interferon regulatory factor-1, NF-kappaB, and PU.1. J Biol Chem, 2006, 281(28):19188-95
    8. Liu J, Malkani G, Shi X, Meyer M, Cunningham-Runddles S, Ma X, Sun ZS. The circadian clock Period 2 gene regulates gamma interferon production of NK cells in host response to lipopolysaccharide-induced endotoxic shock. Infect Immun, 2006, 74(8):4750-4756.
    9. Torroella-Kouri M, Ma X, Perry G, Ivanova M, Cejas PJ, Owen JL, Iragavarapu-Charyulu V, Lopez DM. Diminished expression of transcription factors nuclear factor kappaB and CCAAT/enhancer binding protein underlies a novel tumor evasion mechanism affecting macrophages of mammary tumor-bearing mice. Cancer Res. 2005, 65(22):10578-84.
    10. Shan D, Chen L, Njardarson JT, Gaul C, Ma X, Danishefsky SJ, Huang XY. Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice. Proc Natl Acad Sci U S A. 2005, 102(10):3772-6. 
    11. Murray HW, Flanders KC, Donaldson DD, Sypek JP, Gotwals PJ, Liu J, Ma X. Antagonizing deactivating cytokines to enhance host defense and chemotherapy in experimental visceral leishmaniasis. Infect Immun, 2005, 73(7):3903-3911.
    12. Liu J, Guan X, Ma X. Interferon regulatory factor 1 is an essential and direct transcriptional activator for interferon {gamma}-induced RANTES/CCl5 expression in macrophages. J Biol Chem, 2005, 280(26):24347-24355.
    13. Cao S, Liu J, Song L, Ma X. The protooncogene c-Maf is an essential transcription factor for IL-10 gene expression in macrophages. J Immunol, 2005, 174(6):3484-92.
    14. Shi X, Cao S, Mitsuhashi M, Xiang Z, Ma X. Genome-wide analysis of molecular changes in IL-12-induced control of mammary carcinoma via IFN-gamma-independent mechanisms. J Immunol, 2004, 172(7):4111-22.
    15. Shi X, Liu J, Xiang Z, Mitsuhashi M, Wu RS, Ma X. Gene expression analysis in Interleukin-12-induced suppression of mouse mammary carcinoma. Int J Cancer, 2004, 110(4):570-578.
    16. Mitsuhashi M, Liu J, Cao S, Shi X, Ma X. Regulation of interleukin-12 gene expression and its anti-tumor activities by prostaglandin E2 derived from mammary carcinomas. J Leukoc Biol, 2004, 76(2):322-32. 
    17. Liu J, Guan X, Tamura T, Ozato K, Ma X. Synergistic activation of interleukin-12 p35 gene transcription by interferon regulatory factor-1 and interferon consensus sequence-binding protein. J Biol Chem. 2004, 279(53):55609-17. 
    18. Liu J, Xiang Z, Ma X. Role of IFN regulatory factor-1 and IL-12 in immunological resistance to pathogenesis of N-methyl-N-nitrosourea-induced T lymphoma. J Immunol. 2004, 173(2):1184-93.
    19. Liu J, Cao S, Herman LM, Ma X. Differential regulation of interleukin (IL)-12 p35 and p40 gene expression and interferon (IFN)-gamma-primed IL-12 production by IFN regulatory factor 1. J Exp Med. 2003, 198(8):1265-76.
    20. Kim SJ, Gershov D, Ma X, Brot N, Elkon KB. I-PLA(2) activation during apoptosis promotes the exposure of membrane lysophosphatidylcholine leading to binding by natural immunoglobulin M antibodies and complement activation. J Exp Med 2002, 196(5):655-665.

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