Ping Xu

Ping Xu

Professor

E-mail:pingxu@sjtu.edu.cn

Website:

Phone:pingxu@sjtu.edu.cn

Resume

Dr. Ping Xu graduated from East China University of Science and Technology in 1982 and studied in Japan from 1992 to 1993 in the course of International Post Graduate University Course in Microbiology at Osaka University and Kyoto University. He got a PhD from Shandong University in 1999.  He has been a full professor of State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong Univedrsity since 2008. With the background in chemical engineering and microbiology, Dr. Xu’s research interests are primarily in environmental and chemical biology and “White Biotechnology”. He made the biodegradation more potential by genetic engineering and developing new reasonable idea such as performing biodesufurization of petroleum, constructing the solvent-tolerant desufurizing bacterium and simultaneously degrading of compounds containing sulfur, nitrogen, oxygen atoms. In the environment-friendly biotechnology area, his efforts are made to obtain important products such as pyruvic acid, 2,3-butandiol and sialic acid by bio-catalyses and fermentation. He has also made effort to biotransform the pollutant nicotine into useful products and be successful in production of natural additives and flavours such as acetoin and vanillin etc.

Education Experience

1996.09-1999.07   Ph.D., Department of Microbiology, Shandong University

1992.10-1993.10    International Post -Graduate University Course  in Microbiology held at Osaka Univ. and Kyoto Univ. under the sponsorship of the Japanese Government and UNESCO 

1987.09-1990.07   M.S., Department of Microbiology, Shandong University 

1978.09-1982.07     B.E., Biochemical Engineering, East China University of Science and Technology

Work Experience

2008.04- present  Distinguished professor, deputy director, State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University  

2005.12-2008.04  “Hundred Talents Program” professor, Institute of Microbiology, Chinese Academy of Sciences 

2001.12-2005.03  Deputy director, State Key Laboratory of Microbial Technology, Shandong University 

1997.12-2008.03   Professor, Department of Microbiology, Shandong University 

1994.12-1997.11   Assoc Professor, Department of Microbiology, Shandong University 

1985.10-1994.11   Lecturer, Department of Microbiology, Shandong University 

2003-2004   Senior Visiting Scholar, German Research Centre for Biotechnology 

1997-1998   Senior Visiting Scholar, Department of Chemical Engineering, The Hong Kong University of Science and Technology 

1995-1996   Senior Visiting Scholar, Depart ment of Chemical Engineering, Glamorgan University, UK

Honors

2007: Winner of Young Asian Biotechnologist Prize, the Society for Biotechnology, Japan

2005: Winner of “Hundred Talents Program”, Institute of Microbiology, Chinese Academy of Sciences

2004: Winner of special government allowance, China, 

2002: Winner of cross-century talents cultivation plan, The ministry of education, China

 

1.       Biocatalysis & environmental chemical biology

2.       Bacterial metabolic engineering based on the genomics

3.    Molecular mechanism in degradation of environmental toxins/pollutants

 1.       Chen D, Tang H, Lv Y, Zhang Z, Shen K, Lin K, Zhao YL, Wu G*, Xu P*. Structural and computational studies of the maleate isomerase from Pseudomonas putida S16 reveal a breathing motion wrapping the substrate inside. Mol Microbiol. 2013, 87(6):1237-1244.

2.       Yang W, Tang H, Ni J, Wu Q, Hua D, Tao F  Xu P*. Characterization of two Streptomyces enzymes that convert ferulic acid to vanillin. PLoS ONE. 2013, 8(6):e67339.

3.       Liu XGai ZTao FTang HXu P*. Carotenoids play a positive role in the degradation of heterocycles by Sphingobium yanoikuyae. PLoS ONE 2012, 7(6):e39522.

4.       Tang H, Yao Y, Wang L, Yu H, Ren Y, Wu G, Xu P*. Genomic analysis of Pseudomonas putida: genes in a genome island are crucial for nicotine degradation. Sci Rep. 2012, 2:377.

5.       Tang H, Yao Y, Zhang D, Meng X, Wang L, Yu H, Ma L, Xu P*. A novel NADH-dependent and FAD-containing hydroxylase is crucial for nicotine degradation by Pseudomonas putida. J Biol Chem. 2011, 286(45):39179-39187.

6.       Gao C, Ma C, Xu P*. Biotechnological routes based on lactic acid production from biomass. Biotechnol Adv. 2011, 29(6):930-939.

7.       Hua DXu P*. Recent advances in biotechnological production of 2-phenylethanol. Biotechnol Adv. 2011, 29(6):654-660.

8.       Tao F, Zhang Y, Ma C, Xu P*. One-pot bio-synthesis: N-acetyl-d-neuraminic acid production by a powerful engineered whole-cell catalyst. Sci Rep. 2011, 1:142.

9.       Wang X, Dou P, Zhao P, Zhao C, Ding Y, Xu P*. Immobilization of lipases onto magnetic Fe3O4 nanoparticles for application in biodiesel production. ChemSusChem, 2009, 2(10):947-950.

10.   Li Q, Wang X, Yin G, Gai Z, Tang H, Ma C, Deng Z, Xu P*. New metabolites in dibenzofuran cometabolic degradation by a biphenyl-cultivated Pseudomonas putida strain B6-2. Environ Sci Technol. 2009, 43(22):8635-8642.

11.   Yang C, Wang W, Du M, Li C, Ma C, Xu P*. Pulp mill wastewater sediment reveals novel methanogenic and cellulolytic populations. Water Res. 2013, 47(2):683-692.

12.   Jiang T, Gao C, Dou P, Ma C, Kong J, Xu P*. Rationally re-designed mutation of NAD-independent l-lactate dehydrogenase: high optical resolution of racemic mandelic acid by the engineered Escherichia coli. Microb Cell Fact. 2012, 11:151.

13.   Gai ZWang XLiu XTai CTang HHe XWu GDeng ZXu P*.The genes coding for the conversion of carbazole to catechol are flanked by IS6100 elements in Sphingomonas sp. strain XLDN2-5. PLoS ONE. 2010, 5(4): e10018.

14.   Gao CXu XZhang XChe BMa CQiu JTao FXu P*. Chemoenzymatic synthesis of N-acetyl-d-neuraminic acid from N-acetyl- d-glucosamine using the spore surface displayed N-acetyl- d-neuraminic acid aldolase. Appl Environ Microbiol. 2011, 77(19):7080-7083.

15.   Tang HWang LMeng XMa LWang SHe XWu GXu P*.Novel nicotine oxidoreductase-encoding gene involved in nicotine degradation by Pseudomonas putida strain S16. Appl Environ Microbiol. 2009, 75(3):772-778.

16.   Tang HWang SMa LMeng XDeng ZZhang DMa CXu P*. A novel gene, encoding 6-hydroxy-3-succinoylpyridine hydroxylase, involved in nicotine degradation by Pseudomonas putida strain S16. Appl Environ Microbiol. 2008, 74(5):1567-1574.

17.   Xu P*, Qiu J, Zhang Y, Chen J, Wang P, Yang B, Song J, Xi R, Deng Z, Ma C. Efficient whole-cell biocatalytic synthesis of N-acetyl-d-neuraminic acid. Adv Synth Catal. 2007, 349(10): 1614-1618.

18.   Xu P*Hua DMa C. Microbial transformation of propenylbenzenes for natural flavour production. Trends Biotechnol. 2007, 25(12):571-576

19.   Xiao ZXu P*.Acetoin metabolism in bacteria. Crit Rev Microbiol. 2007, 33(2):127-140.

20.  Xu P*Yu BLi FL, Cai XFMa CQ. Microbial degradation of sulfur, nitrogen and oxygen heterocycles. Trends Microbiol. 2006, 14(9):398-405.

 

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