1.       蛋白质组学和蛋白质翻译后修饰

2.       生物分子的分离分析与生物标志物的发现与验证

3.       重大疾病的无损伤分子诊断

1.         Xiao H*, Zhang L, Zhou H, Lee JM, Garon EB, Wong DT*. Proteomic analysis of human saliva from lung cancer patients using two-dimensional difference gel electrophoresis and mass spectrometry. Mol Cell Proteomics 2012, 11(2):M111.012112.

2.         Xiao H*, Wong DT*. Proteomic analysis of microvesicles in human saliva by gel electrophoresis with liquid chromatography-mass spectrometry. Anal Chim Acta 2012, 723:61-67.

3.         Xiao H*, Wong DT*. Method development for proteome stabilization in human saliva. Anal Chim Acta 2012, 722:63-69.

4.         Zhang L†, Xiao H*†, Zhou H, Santiago S, Lee JM, Garon EB, Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, Park NH, Wong DT*. Development of transcriptomic biomarker signature in human saliva to detect lung cancer. Cell  Mol Life Sci. 2012, 69(19):3341-3350.

5.         Zhang L†, Xiao H†, Karlan S†, Zhou H†, Gross J, Elashoff D, Akin D, Yan X, Chia D, Karlan B, Wong DT. Discovery and preclinical validation of salivary transcriptomic and proteomic biomarkers for the non-invasive detection of breast cancer. PLoS ONE 2010, 5(12):e15573. 
(†:Equal Contribution)