微生物代谢国家重点实验室-科研队伍

张晓君

姓名: 张晓君

职称: 研究员

E-Mail: Xjzhang68@sjtu.edu.cn

个人主页: http://moleco.sjtu.edu.cn/home.htm

联系电话: 021-34204878

个人简历:

（1）教育经历
1990年和1995年在兰州大学生物系分别获学士和硕士学位；
2002年在中科院寒区旱区环境与工程研究所获得博士学位；

（2）工作经历
1995年-1999年，在兰州大学生物系任教（讲师）；
2002年-2004年挪威农业大学（现挪威生命科学大学）化学与生物技术系博士后；
2004年9月开始在上海交通大学生命学院微生物分子生态学与基因组学实验室任副教授，2013年任研究员。
2006年－2007年在法国里昂第一大学微生物生态学实验室(UMR CNRS 5557)访问研究。

（3）学会兼职
     2006年起担任中国微生物学会环境微生物专业委员会委员，上海市微生物学会环境微生物专业委员会委员。
     现任上海市微生物学会常务理事、副秘书长。
     《微生物学通报》、《Applied Environmental Biotechnology》编委
1) 微生物群落的分子生态学与生态基因组学；

2) 有机污染物反硝化降解菌群结构和功能关系研究；

3) 农田土壤系统中反硝化菌群与氮循环关系研究。
涉及工业废水微生物处理过程微生物群落结构与功能分析、功能菌分离、功能基因的克隆、元基因组学、以及农业土壤环境的分子生态学等方面的研究。
1.         Ying Zhu, Xiaoyuan Zhang, Xiaogang Wu, Guanzhou Chen, Lars R. Bakken, Liping Zhao, Åsa Frostegård, Xiaojun Zhang*. Carbon-driven enrichment of the crucial nitrate reducing bacteria in limed peat soil microcosms. Letter in Applied Microbiology. 2017, 65:159-164.

2.         Yang Liuqing，Xiaojun Zhang* & Xiaotang Ju. Linkage between N2O emission and functional gene abundance in an intensively managed calcareous fluvo-aquic soil. Scientific Reports. 2017, 7:43283 | DOI: 10.1038/srep43283.

3.         Dong Wu，Guanzhou Chen, Xiaojun Zhang, Kai Yang & Bing Xie. Change in microbial community in landfill refuse contaminated with antibiotics facilitates denitrification more than the increase in ARG over long-term. Scientific Reports. 2016, 6:24030 | DOI: 10.1038/srep24030.

4.         Yajie Li,   Salma Tabassum,   Zhenjiang Yu,   Xiaogang Wu, Xiaojun Zhang,   Yaping Song,   Chunfeng Chu and Zhenjia Zhang. Effect of effluent recirculation rate on the performance of anaerobic bio-filter treating coal gasification wastewater under co-digestion conditions. RSC Adv., 2016,6, 87926-87934.

5.         Zhang Qianpeng, Wu Yanqiu, Wang Jing, Wu Guojun, Long Wenmin, Xue Zhengsheng,Wang Linghua, Zhang Xiaojun, Pang Xiaoyan, Zhao Yufeng, Zhao Liping, Zhang Chenhong. Accelerated dysbiosis of gut microbiota during aggravation of DSS-induced colitis by a butyrate-producing bacterium, Scientific Reports. 2016, 6:27572 | DOI: 10.1038/srep27572

6.         Guojun Wu, Chenhong Zhang, Jing Wang, Feng Zhang, Ruirui Wang, Jian Shen, Linghua Wang, Xiaoyan Pang, Xiaojun Zhang, Liping Zhao & Menghui Zhang. Diminution of the gut resistome after a gut microbiota-targeted dietary intervention in obese children. Scientific Reports, 2016，24030. doi:10.1038/srep24030.

7.         Wu G, Zhang M, Wei C, Yun Wang, Xiangyu Yao, Liping Zhao and Xiaojun Zhang*. Draft genome sequence of Thauera sp. DTG from a denitrifying quinoline degrading microbial consortium. Applied Environmental and Bitotechnology, 2016, 1(1): 38-43. http://dx.doi.org/10.18063/AEB.2016.01.012.

8.         Guojun Wu, Chenhong Zhang, Jing Wang, Feng Zhang, Ruirui Wang, Jian Shen, Linghua Wang, Xiaoyan Pang, Xiaojun Zhang, Liping Zhao & Menghui Zhang. Diminution of the gut resistome after a gut microbiota-targeted dietary intervention in obese children. Scientific Reports, 2016，24030. doi:10.1038/srep24030.

9.         Joseph Nesme1, Wafa Achouak2, Spiros N. Agathos 3, Mark Bailey 4, Petr Baldrian, Dominique Brunel, Asa Frostegård, Thierry Heulin, Janet K. Jansson, Edouard Jurkevitch, Kristiina L. Kruus, George A. Kowalchuk, Antonio Lagares, Hilary M. Lappin-Scott, Philippe Lemanceau, Denis Le Paslier, Ines Mandic-Mulec, J. Colin Murrell, David D. Myrold, Renaud Nalin, Paolo Nannipieri, Josh D. Neufeld, Fergal O’Gara, John J. Parnell, Alfred Pühler, Victor Pylro, Juan L. Ramos, Luiz F. W. Roesch, Michael Schloter, Christa Schleper, Alexander Sczyrba, Angela Sessitsch, Sara Sjöling, Jan Sørensen, Søren J. Sørensen, Christoph C. Tebbe, Edward Topp, George Tsiamis, Jan Dirk van Elsas, Geertje van Keulen, Franco Widmer, Michael Wagner, Tong Zhang, Xiaojun Zhang, Liping Zhao, Yong-Guan Zhu, Timothy M. Vogel and Pascal Simonet. Back to the Future of Soil Metagenomics. Frontier in Microbiology, 2016, doi: 10.3389/fmicb.2016.00073

10.     Salma Tabassum, Yun Wang, Xiaojun Zhang and Zhenjia Zhang. Novel Mass Bio System (MBS) and its potential application in advanced treatment of coal gasification wastewater. RSC Advances, 2015, 5, 88692-88702. DOI: 10.1039/c5ra11506j. (IF:3.84)

11.     Chenhong Zhang, Aihua Yin, Hongde Li, Ruirui Wang, Guojun Wu, Jian Shen, Menghui Zhang, Linghua Wang, Yaping Hou, Haimei Ouyang, Yan Zhang, Yinan Zheng, Jicheng Wang, Xiaofei Lv, Yulan Wang, Feng Zhang, Benhua Zeng, Wenxia Li, Feiyan Yan, Yufeng Zhao, Xiaoyan Pang, Xiaojun Zhang, Huaqing Fu, Feng Chen, Naisi Zhao, Bruce R. Hamaker, Laura C. Bridgewater, David Weinkove, Karine Clement, Joel Dore, Elaine Holmes, Huasheng Xiao, Guoping Zhao, Shengli Yang, Peer Bork, Jeremy K. Nicholson, Hong Wei, Huiru Tang, Xiaozhuang Zhang, Liping Zhao, Dietary Modulation of Gut Microbiota Contributes to Alleviation of Both Genetic and Simple Obesity in Children, EBioMedicine, 2015, 8(2):968-984, doi:10.1016/j.ebiom.2015.07.007

12.     Xu Zhang, Yufeng Zhao, Jia Xu, Zhengsheng Xue, Menghui Zhang, Xiaoyan Pang, Xiaojun Zhang, and Liping Zhao. Modulation of gut microbiota by berberine and metformin during the treatment of high-fat diet-induced obesity in rats. Scientific Report, 2015, 5, 14405; doi: 10.1038/srep14405.

13. Zhengsheng Xue, Wenping Zhang, Linghua Wang, Rong Hou, Menghui Zhang, Lisong Fei, Xiaojun Zhang, He Huang, Laura C. Bridgewater, Yi Jiang, Chenglin Jiang, Liping Zhao, Xiaoyan Pang, Zhihe Zhang. The bamboo-eating giant panda harbors a carnivore-like gut microbiota, with excessive seasonal variations. mBio. 2015, 6(2):e00022-15. DOI:10.1128/mBio.00022-15 · 6.88 Impact Factor [Show abstract]

14. Ren H, Gao G, Song Z, Wang W, Zhao L, Zhang X* Bacteria in the injection water differently impacts the bacterial communities of production wells in high-temperature petroleum reservoirs. Frontiers in Microbiology, 2015; 6:505. DOI:10.3389/fmicb.2015.00505 · 3.94 Impact Factor. [Show abstract]

15.     Shunzi Xiong,Xia Li, Jianfa Chen, Liping Zhao, Hui Zhang, Xiaojun Zhang*. Crude oil degradation by bacterial consortia under four different redox and temperature conditions. Applied Microbial and Biotechnology, 2015，99(3): 1451-1461. Doi：10.1007/s00253-014-6042-7. ( IF:3.811)

16.     Fei Huang, Ling Ge, Bo Zhang, Yun Wang, Hao Tian, Liping Zhao, Yiliang He, Xiaojun Zhang*. A fullerene colloidal suspension stimulates the growth and denitrification ability of wastewater treatment sludge derived bacteria. Chemosphere, 2014,108:411–417. ( IF:3.137)

17.     Shuiming Xiao, Na Fei, Xiaoyan Pang, Jian Shen, Linghua Wang, Baorang Zhang, Menghui Zhang, Xiaojun Zhang, Chenhong Zhang, Min Li, Lifeng Sun, Zhengsheng Xue, Jingjing Wang, Jie Feng, Feiyan Yan, Naisi Zhao, Jiaqi Liu, Wenmin Long, Liping Zhao. A gut microbiota-targeted dietary intervention for amelioration of chronic inflammation underlying metabolic syndrome, FEMS Microbiology Ecology, 2014, 87(2):357-67. doi: 10.1111/1574-6941.12228.

18.     Yuze Song, Pan Yu, Bailin Li, Yingjie Pan, Xiaojun Zhang, Jian Cong, Yinying Zhao, Hua Wang and Lanming Chen . The mosaic accessory gene structures of the SXT/R391-like integrative and conjugative elements derived from Vibrio spp. isolated from aquatic products and environment in the Yangtze River estuary, China. BMC Microbiology 2013, 13:214. doi:10.1186/1471-2180-13-214

19.     Jie Feng, Huang Tang, Min Li, Xiaoyan Pang, Linghua Wang, Menghui Zhang, Yufeng Zhao, Xiaojun Zhang, Jian Shen*.The abundance of fecal Faecalibacterium prausnitzii in relation to obesity and gender in Chinese adults. Archives of Microbiology, 2013, 196(1):73-7. DOI 10.1007/s00203-013-0942

20.     Xiaojun Zhang*, Jeseph Nesme, Pascal Simonet and Åsa Frostegård. Fate of invading bacteria in soil and survival of transformants after simulated uptake of transgenes, as evaluated by a model system based on lindane degradation. Research in Microbiology, 2012, 163:200-210. 10.1016/j.resmic.2012.01.007
开展了对焦化废水这一难降解工业废水的微生物群落的深入研究，通过以喹啉反硝化降解反应器为模型揭示了菌群结构和特定基因组成及其变化规律；特别关注Thauera属细菌这类重要的污染物分解菌，创建了一套分析Thauera属细菌的方法，为研究重要降解功能菌奠定了良好基础；在分子标识物引导的群落内关键菌群的分离技术方面有所创新，并分离了一批反硝化降解菌，研究了这些降解菌的特性。与挪威农业大学合作研究农田土壤系统中反硝化菌群与氮循环关系，揭示了反硝化基因表达与调控机制。还对油藏极端环境的微生物生态学开展了探索研究，提出一些独特的观点。近年来在国内外刊物上发表论文近百篇。