姓名: 刘昱
职称: 特别研究员
E-Mail: liuyu_sjtu@sjtu.edu.cn
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个人简历:
(1)教育经历
北京师范大学化学专业学士,美国韦恩州立大学分析化学博士,美国国立卫生研究院博士后。
(2)工作经历
研究方向集中在化学与生命科学的交叉领域:开发PLOR方法,实现长链RNA特异标记;结合多种新技术新方法解析RNA的原子级分辨率的三维结构;结合生物化学、合成生物学及分子生物学等手段研究非编码RNA与其它分子之间的相互作用机制及RNA参与基因调控的机理。
发表论文:
1. Stagno, J., Y.Liu*, et. al. Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography. Nature, 2017, 541: 242-246. 2. Y. Liu*, P. Yu, et. al. Applications of PLOR in labeling large RNAs at specific sites. Methods, 2016, 103: 4-10. 3. Y. Liu*, R. Sousa, Y-X. Wang. Specific labeling: An effective tool to explore the RNA world. BioEssays (2016), 38: 192-200 (*: 通讯作者). 4. Y. Liu*, E. Holmstrom, et. al. Synthesis and applications of RNAs with position-selective labeling and mosaic composition. Nature (2015), 522: 368-372. Related Highlights: A machine to manage modifications, Nature Methods (2015), 12: 598-599. 5. X. Fang, et. al., Y. Liu*, et. al. An unusual topological structure of the HIV-1 Rev response element. Cell (2013), 155: 594-605.