丁伟
Wei Ding
长聘教轨副教授
博士生导师
研究重点：
微生物天然产物生物合成和合成生物学
主要从事微生物来源的天然产物发现、生物合成和合成生物学研究；在该领域取得了多个重要的原创性研究成果。在Nature Communications、PNAS、Angewandte Chemie、ACS Chemical Biology等期刊上发表论文近50余篇，相关研究成果被Science、Nature Chemical Biology、Faculty of 1000等多个顶级刊物予以专文亮点评述;申请和授权发明专利近十项。
教育经历
Educational experience
2006-2010：兰州大学生命科学院和中科院上海有机化学研究所联合培养，博士
2001-2005：兰州大学生命科学院，本科
工作经历
Work experience
2019-至今：上海交通大学生命科学技术学院，特别研究员、博导
2013-2018：兰州大学生命科学院，副教授、硕导
2010-2012：德国Saarland University，药物生物技术系，博士后
荣誉获奖
Honours and Awards
代表性论文
Representative works
1. He Li, Wei Ding*, Fen-er Chen*, Qi Zhang*. Light-Driven Reactions Catalyzed by Radical S-Adenosylmethionine Enzymes.ACS Catalysis. 2025 15 (16), 14108-14114.
2. Doudou Dong, Wei Zhang, Wei Ding*.Dichloromethyl-Containing Derivatives from Streptomyces agglomeratus 5-2-6, a Soil Bacterium Isolated from the Qinghai-Tibet Plateau. Journal of Natural Products. 2025 88 (4), 896-906
3. Radical SAM-dependent ether crosslink in daropeptide biosynthesis Sijia Guo, Shu Wang, Suze Ma, Zixin Deng, Wei Ding* and Qi Zhang*. Nature Communications. 2022, doi: 10.1038/s41467-021-44634-a
4. Wei Ding, Wenjuan Ji, Yujie Wu, Runze Wu, Wan-Qiu Liu, Tianlu Mo, Junfeng Zhao, Xiaoyan Ma, Ping Xu, Boping Tang*, Yi Yu* and Qi Zhang*. Biosynthesis of the Nosiheptide Indole Side Ring Centers on a Cryptic Carrier Protein NosJ. Nature Communications. 2017, 8(1):437.
5. Wei Ding, Yongzhen Li, Junfeng Zhao, Xinjian Ji, Tianlu Mo, Haocheng Qianzhu, Zixin Deng, Yi Yu, and Qi Zhang*. Catalytic Mechanism of the Class C radical S-Adenosylmethionine Methyltransferase. Angew. Chem. Int. Ed. 2017, 56, 3857 -3861.
6. Wei Ding, Wan-Qiu Liu, Youli Jia, Yongzhen Li, Wilfred A van der Donk*, and Qi Zhang*. Biosynthetic investigation of phomopsins revealed a widespread pathway for ribosomal natural products in Ascomycetes. Proc. Natl. Acad. Sci. 2016, 113, 3521-3526
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