蹇华哗
Huahua Jian
研究员
博士生导师
研究重点：
环境病毒学
研究员，博士生导师，主要研究方向为环境病毒学，聚焦深海深渊等极端环境体系，致力于解析病毒的生命特征、宿主互作机制、生态功能及演化起源等核心科学问题，并探索其资源化潜力。主持国家自然科学基金项目5项、国家重点研发计划子课题3项；先后参与"蛟龙号"西南印度洋、"奋斗者号"克马德克海沟及蒂阿曼蒂娜海沟等载人深潜科考航次，相关成果获海洋科学技术奖一等奖（排名3/15）。累计发表学术论文60篇，其中以（共同）第一/通讯作者在 Nature Communications (2篇)、ISME Journal (3篇)、iMeta 等期刊发表论文30篇。现任中国生物工程学会噬菌体技术专业委员会委员、上海市微生物学会环境微生物学与海洋微生物学专业委员会委员、上海市生态学学会理事。
教育经历
Educational experience
2006.09-2011.09 厦门大学，生命科学学院，博士
2002.09-2006.07 广西大学，生命科学与技术学院，学士
工作经历
Work experience
2022.01-至今 上海交通大学，生命科学技术学院，研究员
2017.01-2021.12 上海交通大学，生命科学技术学院，副研究员
2014.01-2016.12 上海交通大学，生命科学技术学院，助理研究员
2011.08-2013.12 上海交通大学，生命科学技术学院，博士后
2012.07 - 2012.10 德国莱布尼茨波罗的海研究所（IOW），访问学者
科考经历：
2025.03-2025.05 “奋斗者号”载人深潜蒂阿曼蒂娜海沟航次
2022.11-2022.12 奋斗者号”载人深潜克马德克海沟航次
2014.11-2015.02 “蛟龙号”载人深潜西南印度洋热液区航次
2013.04 - 2013.05 “南海天然气水合物勘查与试采环境评价”航次
荣誉获奖
Honours and Awards
2021 上海交通大学优秀班主任
2019 上海交通大学优秀班主任
2017 简浩然环境微生物学优秀论文奖
2018 2018年度海洋科学技术奖一等奖（3/15）
2017 上海交通大学博士后奖励基金二等奖
2013 Gordon Research Conference – Marine Molecular Ecology, Travel Award
2008 第七届全国微生物学曁第三届全国微生物遗传学青年学者学术研讨会论文交流一等奖
代表性论文
Representative works
1. Yali Hao, Mujie Zhang, Xinjuan Lei, Chengrui Zhu, Taoliang Zhang, Yanping Zheng, Xiang Xiao, Huahua Jian*, PSOSP uncovers pervasive SOS‐independent prophages with distinct genomic and host traits in bacterial genomes, iMeta, 2025, in press.
2. Ting Yang, Mujie Zhang, Yi Yi, Yecheng Wang, Zhiwei Wang, Rui Zhang, Xiang Xiao, Huahua Jian*, Diversity and Evolution of Prokaryotic Viral Lytic Proteins, The ISME Journal, 2025, in press.
3. Yi Yi, Shunzhang Liu, Yali Hao, Qingyang Sun, Xinjuan Lei, Yecheng Wang, Jiahua Wang, Mujie Zhang, Shan Tang, Qingxue Tang, Yue Zhang, Xipeng Liu, Yinzhao Wang, Xiang Xiao, Huahua Jian*, A systematic analysis of marine lysogens and proviruses, Nature Communications, 14:6013, 2023.
4. Mujie Zhang, Yali Hao, Yi Yi, Shunzhang Liu, Qingyang Sun, XIaoli Tan, Shan Tang, Xiang Xiao, Huahua Jian*, Unexplored diversity and ecological functions of transposable phages, The ISME Journal, 17:1015-1028, 2023.
5. Huahua Jian#, Guanpeng Xu#, Yi Yi#, Yali Hao, Yinzhao Wang, Lei Xiong, Siyuan Wang, Shunzhang Liu, Canxing Meng, Jiahua Wang, Yue Zhang, Chao Chen, Xiaoyuan Feng, Haiwei Luo, Hao Zhang, Xingguo Zhang, Lianrong Wang, Zhijun Wang, Zixin Deng, Xiang Xiao*, The origin and impeded dissemination of the DNA phosphorothiation system in prokaryotes, Nature Communications, 12:6382, 2021
6. Huahua Jian#, Yi Yi#, Jiahua Wang#, Yali Hao, Mujie Zhang, Siyuan Wang, Canxing Meng, Yue Zhang, Hongmei Jing, Yinzhao Wang, Xiang Xiao*, Diversity and distribution of viruses inhabiting the deepest ocean on Earth, The ISME Journal, 15:3094-3110, 2021
7. Xixiang Tang#, Libo Yu#, Yi Yi#, Jiahua Wang, Siyuan Wang, Canxing Meng, Shunzhang Liu, Yali Hao, Yue Zhang, Xiaorong Cao, Huahua Jian*, Xiang Xiao*, Phylogenomic analysis reveals a two-stage process of the evolutionary transition of Shewanella from the upper ocean to the hadal zone, Environmental Microbiology, 23(2):744-756, 2021
8. Huahua Jian#, Guanpeng Xu#, Shunzhang Liu#, Yali Hao, Canxing Meng, Jianrong Xu, Yue Zhang, Xipeng Liu, Xiang Xiao*, Multiple mechanisms are involved in repression of filamentous phage SW1 transcription by the DNA-binding protein FpsR, Journal of Molecular Biology, 431:1113-1126, 2019
9. Huahua Jian, Lei Xiong, Guanpeng Xu, Xiang Xiao*, Filamentous phage SW1 is active and influences the transcriptome of the host at high-pressure and low-temperature, Environmental Microbiology Reports, 8(3): 358–362, 2016
10. Huahua Jian, Guanpeng Xu, Yingbao Gai, Jun Xu, Xiang Xiao*, The histone-like nucleoid structuring protein (H-NS) is a negative regulator of the lateral flagellar system in the deep-sea bacterium Shewanella piezotolerans WP3, Applied and Environmental Microbiology, 82(8): 2388-2398, 2016
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