施春雷
Chunlei Shi
教授
博士生导师
农生A楼2-217
021-34205755
clshi@sjtu.edu.cn
研究重点: 食源性致病菌快速检测分型与风险评估;食源性致病菌菌膜形成分子机制;食源性致病菌耐药形成传播机制
上海交通大学农业与生物学院研究员、博士生导师、食品科学与工程系主任。美国康奈尔大学食品科学系博士后。2015年入选中国-新西兰科学家交流计划。主要从事食源性致病菌污染防治方面的基础及应用研究。“十三五”、“十四五”国家重点研发计划项目首席科学家。前后主持国家自然科学基金项目、国家重点研发计划项目等20余项。发表论文153篇,其中SCI收录104篇;参编专著5部;申请发明专利32项,授权18项;制修订国家及行业标准5项。先后获得省部级科技奖励5项。2014年主办“中丹食品安全与食品溯源研讨会”。担任国际期刊Frontiers in Microbiology、Foods和Journal of Food Safety编委。兼任中国食品科学技术学会食品安全与技术标准分会理事、上海市卫健委食品安全风险评估专家委员会风险监测专业委员会委员等。
教育经历
Educational experience
1995-1999 华中农业大学,食品科学与工程,学士
1999-2006 华中农业大学-上海交通大学(硕博连读),生物医药工程(生物技术),博士
工作经历
Work experience
2016-至今,上海交通大学农业与生物学院,研究员
2009-2016,上海交通大学农业与生物学院,副教授
2006-2009,上海交通大学农业与生物学院,讲师
荣誉获奖
Honours and Awards
2015 入选中国-新西兰科学家交流计划
代表性论文
Representative works
• 1) Li J, Hou W, Chang J, Tian X, He M, Zhang Z, Shi C*. (2025) The pivotal role of acnA in linking carbon metabolism to virulence and antimicrobial resistance in methicillin-resistant Staphylococcus aureus. Journal of Antimicrobial Chemotherapy, dkaf317, https://doi.org/10.1093/jac/dkaf317.
• 2) Mai ZF, Li JH, Zhan ZQ, Tian XR, Hou WW, He M, Shi CL*. (2025) Metabolic master switch: pyruvate carboxylase fuels antimicrobial resistance and virulence in foodborne Staphylococcus aureus. Foods, 14: 2566. https://doi.org/10.3390/foods14152566
• 3) Tian XR, Zhang ZF, Chang J, Hou WW, Li JH, Shi CL*. (2025) Driver identification for resistome transmission of food-associated methicillin-resistant Staphylococcus aureus ST398. Food Bioscience, 68: 106517. https://doi.org/10.1016/j.fbio.2025.106517.
• 4) Chang J, Yue M, Zhao G, Tang B*, Shi C*. (2025) Advancements in function recognition of staphyloxanthin and targeted inhibitor development. Current Opinion in Food Science, 63: 101300. https://doi.org/10.1016/j.cofs.2025.101300.
• 5) Zhang ZF, Hu MJ, Arunachalam K, Shi CL*. (2025) Genomics revealed novel chromosomal integration of antimicrobial resistance cluster tet(B), sul2, blaTEM-1B, aph(3'')-Ib, and aph(6)-Id in Salmonella Typhimurium. Foodborne Pathogens and Disease, epub online 16 May 2025. https://doi.org/10.1089/fpd.2024.0172
• 6) Zhang Z, Zhao H, Shi C*. (2025) Clonal spread and genetic mechanisms underpinning ciprofloxacin resistance in Salmonella Enteritidis. Foods, 14: 289. https://doi.org/10.3390/foods14020289
• 7) Shi CL*, Kang SM*. (2024) Foodborne Pathogenic Bacteria: Prevalence and Control-Volume I. Foods, 13(10): 1531.
• 8) Zhang ZF, Shi CL*. (2024) A systematic review of expanding Salmonella enterica serovar Indiana from China: Prevalence, antimicrobial resistance and genomic characterization. Food Bioscience, 62: 105248. https://doi.org/10.1016/j.fbio.2024.105248
• 9) Zhang ZF, Hu MJ, Xu XB, Lv C, Shi CL*. (2024) Dynamic antimicrobial resistance and phylogenomic structure of Salmonella Typhimurium from 2007 to 2019 in Shanghai, China. Microbiology Spectrum, 12(8):e00262-24. https://doi.org/10.1128/spectrum.00262-24
• 10) Zhang ZF, Kuang D, Xu XB, Zhan ZQ, Ren H, Shi CL*. (2024) Dissemination of IncC plasmids in Salmonella enterica serovar Thompson recovered from seafood and human diarrheic patients in China. International Journal of Food Microbiology, 417: 110708. https://doi.org/10.1016/j.ijfoodmicro.2024.110708.
• 11) Chang J, Chen B, Du ZQ, Zhao BW, Li JH, Li ZY, Arunachalam K, Shi T, Wei DQ, Shi CL*. (2024) Eugenol targeting CrtM inhibits the biosynthesis of staphyloxanthin in Staphylococcus aureus. Food Science and Human Wellness, 13(03):1368-1377. https://doi.org/10.26599/FSHW.2022.9250115.
• 12) Chang J, Zhang Y, Zhang ZF, Chen B, He SK, Zhan ZQ, Zhong N, Tian XR, Kang SM, Arunachalam K, Shi CL*. (2023) Prevalence, antimicrobial resistance, and genetic characteristics of Staphylococcus aureus isolates in frozen flour and rice products in Shanghai, China. Current Research in Food Science, 7:100631. https://doi.org/10.1016/j.crfs.2023.100631.
• 13) Arunachalam K, Ravi J, Tian XR, Shunmugiah KP, Shanmugaraj G*, Shi C*. (2023) Antibacterial activity of 2-hydroxy-4-methoxybenzaldehyde and its possible mechanism against Staphylococcus aureus. Journal of Applied Microbiology,134(7):lxad144. https://doi.org/10.1093/jambio/lxad144
• 14) Arunachalam K, Krishnan GP, Sethuraman S, Sybiya VP, Thirukannamangai KS, Aakhansha V, Arunkumar J, Shi C*, MubarakAli D*. (2023) Exploring the possible ways to enhance the potential and use of natural products through nanotechnology in the battle against the biofilms of foodborne bacterial pathogens. Pathogens, 12(2): 270.
• 15) Arunachalam K, Poonguzhali P, Shi C*, Lagoa R* (2023) Regulation of Staphylococcus aureus virulence and application of nanotherapeutics to eradicate S. aureus infection. Pharmaceutics, 15(2): 310.
• 16) Hou WW, Kang SM, Chang J, Tian XR, Shi CL*. (2022) Correlation analysis between GlpQ-regulated degradation of wall teichoic acid and biofilm formation triggered by lactobionic acid in Staphylococcus aureus. Foods, 11(21): 3438. https://doi.org/10.3390/ foods11213438
• 17) Zhang ZF, Tian XR, Shi CL*. (2022) Global spread of MCR-producing Salmonella enterica isolates. Antibiotics-Basel, 11(8): 998. https://doi.org/10.3390/antibiotics11080998
• 18) Zhang ZF, Zhan ZQ, Shi CL*. (2022) International spread of Tet(X4)-producing Escherichia coli isolates. Foods, 11(14): 2010. https://doi.org/10.3390/foods11142010
• 19) Martinengo P, Kannappan A, Shi C*. (2021) Polyphenolic Antibacterials for Food Preservation: review, challenges and current applications. Foods, 10: 2469.
• 20) Shang DQ, Zhao H, Xu XB, Kannappan A, Chang J, Bai L, Shi CL*. (2021) Conjugative IncHI2 plasmid harboring novel class 1 integron mediated dissemination of multidrug resistance genes in Salmonella Typhimurium. Food Control, 122: 107810. doi: 10.1016/j.foodcont.2020.107810.
• 21) Ou CJ, Shang DQ, Yang JX, Chen B, Chang J, Jin FN, Shi CL*. (2020) Prevalence of multidrug-resistant Staphylococcus aureus isolates with strong biofilm formation ability among animal-based food in Shanghai. Food Control, 112: 107106. doi: 10.1016/j.foodcont.2020.107106.
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