1999.09-2003.06 山东农业大学生物技术专业，本科，获学士学位

  （作物生物学国家重点实验室）

2003.09-2008.06 山东大学微生物学，硕博连读，获博士学位

  （微生物技术国家重点实验室）

2021-至今 上海交大微生物代谢全国重点实验室，长聘教授

2014-2021 上海交大微生物代谢全国重点实验室，教授（破格晋升）

2011-2014 上海交大微生物代谢全国重点实验室，副研究员

（2012.12-2013.12 美国麻省理工学院 Media Lab，访问学者）

2008-2011 上海交大生命科学技术学院，讲师

1. 上海市优秀学术带头人(2020，No. 20XD1421900);
2. 上海市曙光学者(2017，No. 17SG09);
3. 上海市青年科技启明星(2013，No. 13QA1401700);
4. 上海市晨光学者(2010，No. 10CG10)；
5. 2022年教育部技术发明二等奖（排名第一）
6. 2021年获得发明协会-第十二届“发明创业奖·人物奖”
7. 2021年获得发明协会-发明创业奖-创新奖-二等奖
8. 2020年获得中国产学研合作促进会-产学研合作创新（个人）奖
9. 2016年获得教育部自然科学一等奖（排名第二）

1. Su C.†., Cui H. T.†., Wang W. W.†., Liu Y., Cheng Z. Y., Wang C., Yang M. Q., Qu L. W., Li Y., Cai Y. J., He S. Y., Zheng J X., Zhao P. P., Xu P., Dai J. B.*, and Tang H. Z.*. 2025. Bioremediation of complex organicpollutants by engineered Vibrio natriegens. Nature, 1-10. https://doi.org/10.1038/s41586-025-08947-7.
2. Liu G. Q†., Zhao Y. L†., He F. Y., Zhang P., Ouyang X. Y., Tang H. Z.*, and Xu P. 2021. Structure-guided insights into heterocyclic ring-cleavage catalysis of the non-heme Fe (II) dioxygenase NicX. Nat. Commun. 12(1301): 1-10.
3. Huang Y. Q., Wen L. Y., Zhang L. G., Xu J. J., Wang W. W., Hu H. Y., Xu P., Li Z., and Tang H. Z.*. 2023. Community-integrated multi-omics facilitates screening and isolation of the organohalide dehalogenation microorganism. The Innovation 4(1):100355, 1-8.
4. Liu H., Zhang LG., Wang W. W., Hu H. Y., Ouyang X. Y., Xu P., and Tang H. Z.*. 2023. An intelligent synthetic bacterium for chronological toxicant detection, biodegradation, and its subsequent suicide. Adv. Sci. 2304348:1-11.
5. Ouyang X. Y., Liu G. Q., Ji S. J., Luo S. G., Shi T., Xu P., Zhao Y. L.*, and Tang H. Z.*. 2023. Dioxetane and lactone pathways in dioxygenolytic ring cleavage catalyzed by 2,5-dihydroxypyridine 5,6-dioxygenase. Chem Catal. 3:1-20.
6. Hu H. Y.†., Xu Z. Y.†., Zhang Z. Y., Song P. Z., Stull F., Xu P., Hongzhi Tang and Tang H. Z.*. 2024. Rational design of a flavoenzyme for aerobic nicotine catabolism. mBio 15(10):1-20.
7. Guo L. H.†, Ouyang X. Y.,† Wang W. W., Qiu X. Y., Zhao Y. L., Xu P., and Tang H. Z.*. 2024. Fine-tuning an aromatic ring-hydroxylating oxygenase to degrade high molecular weight polycyclic aromatic hydrocarbon. J. Biol. Chem. 300(6):1-12.
8. Qiu X. Y. †, Wang W. W.†, Zhang L. G., Guo Li. H., Xu P., and Tang H. Z.*. 2022. A thermophile Hydrogenibacillus sp. strain efficiently degrades environmental pollutants PAHs. Environ. Microbiol. 24(1):436-450
9. Wang W. W†., Li Q. G.†, Zhang L. G., Cui J., Yu H., Wang X. Y., Ouyang X. Y., Tao F., Xu P., and Tang H. Z.*. 2021. Genetic mapping of highly versatile and solvent-tolerant Pseudomonas putida B6-2 (ATCC BAA-2545) as a ‘superstar' for mineralization of PAHs and dioxin-like compounds. Environ. Microbiol. 23(8):4309-4325.
10. Zhou Z. K†., Tang H. Z.†*, Wang W. W., Zhang L. G., Su F., Wu Y. T., Bai L. Q., Li S. C., Yuhui Sun Y. H., Tao F., and Xu P*. 2021. A cold shock protein promotes high-temperature microbial growth through binding to diverse RNA species. Cell Discov. 7:1-12.