上海交通大学生命科学技术学院副研究员，博士生导师；上海交通大学理学博士，美国加州大学圣迭戈分校访问学者。研究聚焦糖代谢、能量代谢在生理稳态和疾病发生过程中的作用机制。作为项目负责人主持国家自然科学基金和上海市自然科学基金4项、上海交通大学医工交叉项目2项；以第一作者或通讯作者在PNAS (2021, 2023)、Natl Sci Rev和Cell Mol Life Sci等期刊发表SCI论文16篇，论文总引用次数1380余次；作为副主编出版专著1部，参编出版了学术专著2部；获教育部“国家级一流本科课程奖”，2次获上海交通大学“晨星优秀青年学者”奖；获”第十九届中国青年女科学家”个人奖提名。
2009.09–2015.06，上海交通大学，生命科学技术学院生物学，博士
2005.09–2008.03，上海交通大学，生命科学技术学院生物化工，硕士
2001.09–2005.06，上海海洋大学，食品学院生物制药，学士
2018.12-至今, 上海交通大学，生命科学技术学院，副研究员
2016.11–2017.12, 美国加利福尼亚大学圣迭戈分校（UCSan Diego）医学院, 访问学者
2015.12–2018.12, 上海交通大学，生命科学技术学院，助理研究员
2011.01–2015.12, 上海交通大学，生命科学技术学院，实验师
2008.04–2010.12, 上海交通大学，生命科学技术学院，助理实验师
2023年, 国家级一流本科生课程（线下）
2018、2012年, 上海交通大学，晨星优秀青年学者奖
1. Zou M, Ye K, Yan J, Zhang S, Bao H, Li Z, Tao Y, Zhang X, Tian W, Qi Y, Huo YL, Han Y*. PGC1α regulates the mitochondrial metabolism response to cyclic stretch, which inhibits neointimal hyperplasia. Cell Mol Life Sci, 82:303, 2025.
2. Han Y*, Yan J, Li ZY, Fan YJ, Jiang ZL, Shyy JY*, and Shu Chien*. Cyclic stretch promotes vascular homing of endothelial progenitor cells via Acsl1 regulation of mitochondrial fatty acid oxidation. PNAS, 120 (6): e2219630120, 2023.
3. Yan J, Fan YJ, Bao H, Li YG, Zhang SM, Yao QP, Huo YL, Jiang ZL, Qi YX, Han Y*. Platelet-derived microvesicles regulate vascular smooth muscle cell energy metabolism via PRKAA after intimal injury. J Cell Sci, 135 (7): jcs259364, 2022.
4. Han Y, He M, Marin T, Shen H, Wang WT, Lee TY, Hong HC, Jiang ZL, Garland T, Shyy JY, Gongol B, and Shu Chien. Roles of KLF4 and AMPK in the inhibition of glycolysis by pulsatile shear stress in endothelial cells. PNAS, 118(21): e2103982118, 2021.
5. Feng Y, Wang X, Zhao Y, Li L, Niu P, Huang Y, Han Y*, Tan W, Huo Y*. A comparison of passive and active wall mechanics between elastic and muscular arteries of juvenile and adult rats. J Biomech, 126: 110642, 2021.
6. Yan J, Wang WB, Fan YJ, Bao H, Li N, Yao QP, Huo YL, Jiang ZL, Qi YX, Han Y*. Cyclic stretch induces vascular smooth muscle cells to secrete connective tissue growth factor and promote endothelial progenitor cell differentiation and angiogenesis. Front Cell Dev Biol, 8: 606989, 2020.
7. Yan J, Bao H, Fan YJ, Jiang ZL, Qi YX, Han Y*. Platelet-derived microvesicles promote endothelial progenitor cell proliferation in intimal injury by delivering TGF-β1. FEBS J, 287 (23): 5196-5217, 2020.
8. Wang WB, Li HP, Yan J, Zhuang F, Bao M, Liu JT, Qi YX, Han Y*. CTGF regulates cyclic stretch-induced vascular smooth muscle cell proliferation via microRNA-19b-3p. Exp Cell Res, 376: 77-85, 2019.
9. Li N, Wang WB, Bao H, Shi Q, Jiang ZL, Qi YX, Han Y*. MicroRNA-129-1-3p regulates cyclic stretch–induced endothelial progenitor cell differentiation by targeting Runx2. J Cell Biochem, 120 (4): 5256-5267, 2019.
10. Han Y, Huang K, Yao QP, ZL Jiang. Mechanobiology in vascular remodeling. Natl Sci Rev, 5: 933–946, 2018.
11. Zhang P#, Han Y#, Lu HL, Zhang CM, Song NN, Qi YX, Xu WX, Jiang ZL. Aortic vascular reactivity to angiotension II is modulated by down-regulation of TRPC in renal hypertensive rats. Int J Clin Exp Pathol, 9(11):11003-11013, 2016.
12. Han Y, Wang L, Yao QP, Zhang P, Liu B, Wang GL, Shen BR, Cheng BB, Wang YX, Jiang ZL, Qi YX. Nuclear envelope proteins Nesprin2 and LaminA regulate proliferation and apoptosis of vascular endothelial cells in response to shear stress. BBA Mol Cell Res, 1853(5): 1165-1173, 2015.
13. Wang L#, Han Y#, Shen Y, Yan ZQ, Zhang P, Yao QP, Shen BR, Gao LZ, Qi YX, Jiang ZL. Endothelial insulin-like growth factor-1 modulates proliferation and phenotype of smooth muscle cells induced by low shear stress. Ann Biomed Eng, 42(4):776-86, 2014.
14. Han Y, Pan JS, Wang XL, Qi YX, Wang SW, Yan ZQ. Cyclic strain promotes migration and proliferation of human periodontal ligament cell via PI3K signaling pathway. Cell Mol Bioeng, 3(4): 369-375, 2010.
15. Han Y, Yang BJ, Zhang FL, Miao XL, Li ZY. Characterization of antifungal chitinase from marine Streptomyces sp. DA11 associated with South China Sea sponge Craniella australiensis. Mar Biotechnol, 11(1): 132-140, 2009.
16. Han Y, Li ZY, Miao XL, Zhang FL. Statistical optimization of medium components to improve the chitinase activity of Streptomyces sp. Da11 associated with the South China Sea sponge Craniella australiensis. Process Biochem, 43(10):1088-109, 2008.
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